http://www.medscape.com/viewarticle/563997?src=mpnewsözet:
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=17923594&ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum...
Of the 8499 individuals who did not have coronary heart disease (CHD) at the beginning of the study and who provided sufficient information for analysis, 589 reported a CHD event.
After adjustment for a number of factors, including sociodemographic, biological (obesity, hypertension, diabetes, and cholesterol levels), and health behaviors (smoking, alcohol intake, exercise, and fruit and vegetable consumption), they found that people who experienced negative aspects of a close relationship had a 34% higher risk of incident coronary events (hazard ratio 1.34; 95% CI 1.10-1.63) than those who did not.
The association was attenuated but remained significant after additional adjustment for negative affectivity and depression (HR 1.25).
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